Reo Za Kaindo Wāurufu

Reo za Kaindo Wāurufu (レオ・ザ・カインド・ワーウルフ, lit. Reo the Kind Werewolf) is a 66 episode anime series created by Japanese studio, Andromeda Animation that first aired in 1979 and ended the following year.

Plot
The series is about a little girl, Reo, whose parents had abandoned her after she was born, who begins to turn into a werewolf at night on her twelfth birthday. Shocked and wondering why she turned into a werewolf, she ran away from the orphanage and went out into the wild searching for answers, and her long-lost parents. Along the way, she meets some new animal friends, which she has the ability to communicate with in her werewolf form.

Full Synopsis
In an orphanage outside of a nearby forest, Reo, a girl whose parent's abandoned her after her birth, is about to celebrate her twelfth birthday, but the unnamed owners of the orphanage ruin it for her.