List of Dan & Marilyn characters

Main

 * Kenny Hulings as Daniel "Dan" Henriksen. A devout Christian, he is a vlogger and aspiring Christian rock singer. He is cheerful and kind-hearted, and tends to be very compassionate and forgiving towards others.
 * Amanda Stansby as Marilyn Baxter. Dan's girlfriend, she tends to be sassy, yet often kind. Marilyn grew up attending the same church as Dan. A gymnast, she also has a eccentric variety of interests like her boyfriend, including art, science fiction works and antiquing.
 * Corey L. Moore as Joseph Gershon, Dan and Marilyn's longtime friend. He enjoys music, particularly blues rock, and plays guitar, and often spends his time writing songs or goofing around. He is Jewish.
 * Latanya Bonds as Jessica Mack, an African-American friend of Dan and Marilyn. She works at her dad's bowling alley and hopes one day to be on the Olympic fencing team.
 * Craig Campobello as Todd Hailey, a friend of Dan since his childhood.
 * Rosalia Sosa-Chihuán as Ana Valderrama, a friend of Marilyn from her gymnastics school. She is a lesbian.
 * Akueni Sofoluwe as Folakemi "Kim" Bakare. Originally from, , she has known Dan and Marilyn since middle school. She is an aspiring musician and occasionally plays music with Joseph.
 * Britney Hynes as Samantha "Sammy" Grenville. She attends the same gymnastics school as Marilyn, and is in a relationship with Todd.
 * Marcus Boyd as Spencer Mack, Jessica's younger brother.
 * Heather Chau as Teagan Huang, a gymnastics buddy of Marilyn.
 * Jake Haverkamp as Jacob "Jake" Henry. A friend of Dan, he is an aspiring musician and often plays music together with Joseph. He moved to, in season 4 of Trisha's Way and occasionally visited Dan in Quincy before moving back sometime before the events of Dan & Marilyn began, now having picked up a Southern accent from his time in the city and with a complete change in personality, being more composed, "chill" and mild-mannered than he was originally.
 * Shalisa Acosta as Maryanne Mendoza, Jake's girlfriend. She is Filipino-American.
 * Katelyn Aytoni as Francine Tatros, a friend of Marilyn since daycare. She is of Syrian ancestry and has relatives who were displaced by the civil war. Her parents own a local drive-in restaurant. She is an accomplished figure skater with several regional wins under her belt, and once competed in the Youth Olympics.

Recurring

 * as Jessica Hailey, Todd's older sister who sometimes accompanies Dan and his friends.
 * Daphne Abbagnale as Norma Hailey, Todd's younger sister.
 * Debbie Hulings as April Henriksen, Dan's older sister.
 * Cynthia Heath as Rosie Henriksen, Dan's other older sister.
 * Jeff Matuschek as Dennis Henriksen, Dan's older brother and April's twin brother.
 * G. Fredrick Lyon as Paul Henriksen, Dan's father, a longtime musician who is a minister at the church Dan and Marilyn attend. He is originally from . Lyon reprises the role from Trisha's Way.
 * Georgina Detmold as Jolie Henriksen, Dan's mother.
 * as Frank Baxter, Marilyn's father. The character was previously voiced by Brett McKnight in Trisha's Way.
 * Jane Searle as Shannon Baxter, Marilyn's mother.
 * Stephen Verheijen as Norman Hailey, Todd's father.
 * Costanza Myers as Juliette Hailey, Todd's mother.
 * Stan Barber as Frank "Frankie" Hailey, Todd's older brother.
 * as Lena Tatros, Francine's cousin who works at Francine's dad's restaurant.
 * as Josie Grenville, Sammy's younger sister.
 * Amita Vinjamuri as Meghna Jethmalani, an Indian-American friend of Dan and Marilyn.
 * as Georgia Hailey, Todd's aunt.
 * as Jeremy Meijers, Marilyn's uncle-in-law who is a businessman. In season 3, he becomes a Congressman.
 * as a fictionalized version of himself who is Sammy and Josie's uncle-in-law. He often serves as a source of advice for Sammy and/or the gang.