An American Tail: The Treasure of Manhattan Island: The Video Game Is A 2000 Video Game.
- Thomas Dekker as Fievel Mousekewitz
- Pat Musick as Tony Toponi, and Jack
- Dom DeLuise as Tiger
- Sherman Howard as Chief McBrusque, and Haggis
- John Kassir as Scuttlebutt, Fiddlesticks, Ferdy, Cyrus, and Nightmare Scuttlebutt
- Nehemiah Persoff as Papa Mousekewitz
- Ron Perlman as Mr. Grasping
- Tony Jay as Toplofty
- Richard Karron as O'Bloat
- It Was Based on Film, An American Tail: The Treasure of Manhattan Island.
- It Was Footage From Fievel and Tony.
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