Enzo Bonelli is the leader of a powerful, unspecified crime family that operates in Los Santos, who used his criminal connections to become a real estate developer by securing the majority of all city contracts through extortion, murder and labor racketeering. His hostile takeover left most of the city's older real estate firms in ruins, including Gold Coast Developements, a firm in which Lester Crest has a great sum of personal stock.
To keep Gold Coast from going under, Lester hires Franklin Clinton to assassinate Bonelli at his construction site in Downtown Los Santos. However, Lester's contact within Bonelli's organization betrays him and informs Bonelli of the upcoming hit, leading the mobster to tighten security in the building. Nonetheless, Franklin shoots his way through the guards at the construction site and catches up to Bonelli as he is trying to escape in a helicopter. Franklin kills the last of Bonelli's men and shoots down the helicopter, causing Bonelli to be killed in the ensuing crash and explosion.
After Bonelli's death, the stock for Gold Coast Developments receives a massive bump in share prices.